EMD-4620

Single-particle
26.4 Å
EMD-4620
3D View Gallery
Deposition: 19/02/2019
Map released: 25/03/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4620
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A dimer component of alpha-1 antitrypsin heat-induced polymers generated from wild-type M plasma protein and decorated with Fab 4B12

EMD-4620

Single-particle
26.4 Å
EMD-4620
3D View Gallery
Deposition: 19/02/2019
Map released: 25/03/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Polymers induced by heating monomeric wild-type alpha-1 antitrypsin and labelled with 4B12 Fab fragments

Deposition Authors: Elliston ELK, Redzej A, Orlova EV, Lomas DA, Irving JA
The structural basis for Z alpha 1 -antitrypsin polymerization in the liver.
Faull SV , Elliston ELK , Gooptu B , Jagger AM , Aldobiyan I, Redzej A , Badaoui M , Heyer-Chauhan N , Rashid ST , Reynolds GM , Adams DH , Miranda E, Orlova EV , Irving JA , Lomas DA
(2020) Sci Adv , 6
PUBMED: 33087346
DOI: doi:10.1126/sciadv.abc1370
ISSN: 2375-2548