EMD-46048
HIV Env ZM233 NFL TD CC3+ trimer in complex with NHP #1,2,3,4 polyclonal Fab (gp41-FP, gp41-base epitopes)
EMD-46048
Single-particle27.0 Å
Deposition: 02/08/2024Map released: 28/05/2025
Last modified: 25/06/2025
Sample Organism:
Macaca mulatta
Sample: HIV Env ZM233 NFL TD CC3+ trimer in complex with NHP #1,2,3,4 polyclonal Fab (gp41-FP, gp41-base epitopes)
Deposition Authors: Sewall LM
,
Ozorowski G ,
Ward AB
Sample: HIV Env ZM233 NFL TD CC3+ trimer in complex with NHP #1,2,3,4 polyclonal Fab (gp41-FP, gp41-base epitopes)
Deposition Authors: Sewall LM
,
Ozorowski G ,
Ward AB
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer.
Schleich FA ,
Bale S,
Guenaga J,
Ozorowski G ,
Adori M,
Lin X,
Castro Dopico X ,
Wilson R,
Chernyshev M,
Cotgreave AT,
Mandolesi M,
Cluff J,
Doyle ED,
Sewall LM ,
Lee WH,
Zhang S,
O'Dell S,
Healy BS,
Lim D,
Lewis VR,
Ben-Akiva E,
Irvine DJ,
Doria-Rose NA,
Corcoran M,
Carnathan D,
Silvestri G,
Wilson IA,
Ward AB ,
Karlsson Hedestam GB,
Wyatt RT
(2025) Immunity , 58 , 1598 - 1613.e8
,
Bale S,
Guenaga J,
Ozorowski G ,
Adori M,
Lin X,
Castro Dopico X ,
Wilson R,
Chernyshev M,
Cotgreave AT,
Mandolesi M,
Cluff J,
Doyle ED,
Sewall LM ,
Lee WH,
Zhang S,
O'Dell S,
Healy BS,
Lim D,
Lewis VR,
Ben-Akiva E,
Irvine DJ,
Doria-Rose NA,
Corcoran M,
Carnathan D,
Silvestri G,
Wilson IA,
Ward AB ,
Karlsson Hedestam GB,
Wyatt RT
(2025) Immunity , 58 , 1598 - 1613.e8
Grant Support: