Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-46041

Single-particle
2.7 Å
EMD-46041
3D View Gallery
Deposition: 02/08/2024
Map released: 13/08/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46041
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cye summary report (pdf.gz) Map and 9cye FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of DA03E17 Fab in complex with influenza virus neuraminidase from A/California/07/2009 (H1N1)

EMD-46041

Single-particle
2.7 Å
EMD-46041
3D View Gallery
Deposition: 02/08/2024
Map released: 13/08/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Influenza A virus (A/California/07/2009(H1N1))
Sample: DA03E17 Fab in complex with influenza virus neuraminidase from A/California/07/2009 (H1N1)
Fitted models: 9cye

Deposition Authors: Jo G , Ward AB
Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3.
Jo G , Yamayoshi S , Ma KM , Swanson O , Torres JL , Ferguson JA, Fernandez-Quintero ML, Huang J, Copps J , Rodriguez AJ, Steichen JM, Kawaoka Y , Han J , Ward AB
(2025) Nat Commun , 16 , 7067 - 7067
PUBMED: 40750588
DOI: doi:10.1038/s41467-025-62174-2
ISSN: 2041-1723