EMD-46005

Single-particle
3.2 Å
EMD-46005
3D View Gallery
Deposition: 01/08/2024
Map released: 16/04/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46005

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cy3 summary report (pdf.gz) Map-9cy3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Outward-facing Atorvastatin-bound OATP1B1 with sybody Sb5

EMD-46005

Single-particle
3.2 Å
EMD-46005
3D View Gallery
Deposition: 01/08/2024
Map released: 16/04/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Outward-facing atorvastatin-bound OATP1B1 with Sybody 5
Fitted models: 9cy3

Deposition Authors: Sung MW, Lees JA , Han S
Cyclosporine A sterically inhibits statin transport by solute carrier OATP1B1.
Sung MW, Hu K, Hurlimann LM, Lees JA , Fennell KF, West MA, Costales C , Rodrigues AD, Zimmermann I , Dawson RJP, Liu S, Han S
(2025) J Biol Chem , 301 , 108484 - 108484
PUBMED: 40199401
DOI: doi:10.1016/j.jbc.2025.108484
ISSN: 1083-351X
ASTM: JBCHA3
Grant Support: