EMD-45979

Helical reconstruction
3.2 Å
EMD-45979
3D View Gallery
Deposition: 30/07/2024
Map released: 14/08/2024
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45979

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cx6 summary report (pdf.gz) Map-9cx6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM filament structure in FTLD-synuclein

EMD-45979

Helical reconstruction
3.2 Å
EMD-45979
3D View Gallery
Deposition: 30/07/2024
Map released: 14/08/2024
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha-synuclein filaments extracted from the human brain with multiple system atrophy
Fitted models: 9cx6

Deposition Authors: Yang Y , Scheres HWS, Goedert M
Identical Seeding Characteristics and Cryo-EM Filament Structures in FTLD-Synuclein and Typical Multiple System Atrophy.
Cullinane PW , Yang Y , Chelban V , Goh YY, Ebanks K, Curless T, Wrigley S, de Pablo-Fernandez E, Holton J, Peak-Chew S, Franco C , Woerman AL, Houlden H, Warner TT, Scheres SHW, Goedert M, Jaunmuktane Z
(2025) Neuropathol Appl Neurobiol , 51 , e70013 - e70013
PUBMED: 40135351
DOI: doi:10.1111/nan.70013
ISSN: 1365-2990