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EMD-45928
LJF-085 Fab in complex with HIV Env JRFL NFL TD CC3+ trimer and 35O22 Fab
EMD-45928
Single-particle3.4 Å
Deposition: 25/07/2024Map released: 21/05/2025
Last modified: 25/06/2025
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens,
Macaca mulatta
Sample: LJF-085 Fab in complex with HIV Env JRFL NFL TD CC3+ trimer and 35O22 Fab
Fitted models: 9cu5
Deposition Authors: Ozorowski G, Ward AB
Sample: LJF-085 Fab in complex with HIV Env JRFL NFL TD CC3+ trimer and 35O22 Fab
Fitted models: 9cu5
Deposition Authors: Ozorowski G, Ward AB
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer.
Schleich FA,
Bale S,
Guenaga J,
Ozorowski G,
Adori M,
Lin X,
Castro Dopico X 
,
Wilson R,
Chernyshev M,
Cotgreave AT,
Mandolesi M,
Cluff J,
Doyle ED,
Sewall LM,
Lee WH,
Zhang S,
O'Dell S,
Healy BS,
Lim D,
Lewis VR,
Ben-Akiva E,
Irvine DJ,
Doria-Rose NA,
Corcoran M,
Carnathan D,
Silvestri G,
Wilson IA,
Ward AB,
Karlsson Hedestam GB,
Wyatt RT
(2025) Immunity , 58 , 1598
,
Wilson R,
Chernyshev M,
Cotgreave AT,
Mandolesi M,
Cluff J,
Doyle ED,
Sewall LM,
Lee WH,
Zhang S,
O'Dell S,
Healy BS,
Lim D,
Lewis VR,
Ben-Akiva E,
Irvine DJ,
Doria-Rose NA,
Corcoran M,
Carnathan D,
Silvestri G,
Wilson IA,
Ward AB,
Karlsson Hedestam GB,
Wyatt RT
(2025) Immunity , 58 , 1598
Grant Support: