EMD-45792

Single-particle
2.7 Å
EMD-45792
3D View Gallery
Deposition: 17/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45792

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Constituent EM map: focused refinement of the Venus flytrap (VFT) and cysteine-rich (CRD) domains of the calcium-sensing receptor.

EMD-45792

Single-particle
2.7 Å
EMD-45792
3D View Gallery
Deposition: 17/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Calcium-sensing receptor bound to compound '6218

Deposition Authors: Wu C, Skiniotis G
Large library docking identifies positive allosteric modulators of the calcium-sensing receptor.
Liu F , Wu CG , Tu CL, Glenn I, Meyerowitz J, Kaplan AL , Lyu J , Cheng Z, Tarkhanova OO , Moroz YS , Irwin JJ , Chang W , Shoichet BK , Skiniotis G
(2024) Science , 385 , eado1868 - eado1868
PUBMED: 39298584
DOI: doi:10.1126/science.ado1868
ISSN: 1095-9203
ASTM: SCIEAS