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EMD-45792

Single-particle
2.7 Å
EMD-45792
3D View Gallery
Deposition: 17/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45792
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Constituent EM map: focused refinement of the Venus flytrap (VFT) and cysteine-rich (CRD) domains of the calcium-sensing receptor.

EMD-45792

Single-particle
2.7 Å
EMD-45792
3D View Gallery
Deposition: 17/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Calcium-sensing receptor bound to compound '6218

Deposition Authors: Wu C, Skiniotis G
Large library docking identifies positive allosteric modulators of the calcium-sensing receptor.
Liu F , Wu CG , Tu CL, Glenn I, Meyerowitz J, Kaplan AL , Lyu J , Cheng Z, Tarkhanova OO , Moroz YS, Irwin JJ , Chang W , Shoichet BK , Skiniotis G
(2024) Science , 385 , eado1868 - eado1868
PUBMED: 39298584
DOI: doi:10.1126/science.ado1868
ISSN: 1095-9203
ASTM: SCIEAS