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EMD-45732

Composite map
Single-particle
3.19 Å
EMD-45732
3D View Gallery
Deposition: 12/07/2024
Map released: 25/06/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45732
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9clw summary report (pdf.gz) Map and 9clw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of Gq-coupled FFA2 in complex with TUG-1375 and 4-CMTB

EMD-45732

Composite map
Single-particle
3.19 Å
EMD-45732
3D View Gallery
Deposition: 12/07/2024
Map released: 25/06/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: TUG-1375-4-CMTB-FFA2-miniGq complex
Fitted models: 9clw

Deposition Authors: Zhang X , Tikhonova I, Milligan G , Zhang C
Allosteric modulation and biased signalling at free fatty acid receptor 2.
Zhang X , Guseinov AA , Jenkins L , Valentini A, Marsango S, Schultz-Knudsen K, Ulven T , Rexen Ulven E , Tikhonova IG , Milligan G , Zhang C
(2025) Nature , 643 , 1428 - 1438
PUBMED: 40533560
DOI: doi:10.1038/s41586-025-09186-6
ISSN: 1476-4687
ASTM: NATUAS