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EMD-45616

Single-particle
2.62 Å
EMD-45616
3D View Gallery
Deposition: 03/07/2024
Map released: 14/05/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45616
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cib summary report (pdf.gz) Map and 9cib FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413 (Local Refinement)

EMD-45616

Single-particle
2.62 Å
EMD-45616
3D View Gallery
Deposition: 03/07/2024
Map released: 14/05/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse HCAD-Gai1 in complex with FCH-2296413
Fitted models: 9cib

Deposition Authors: Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL
Structure-guided design of a peripherally restricted chemogenetic system.
Kang HJ, Krumm BE, Tassou A, Geron M, DiBerto JF, Kapolka NJ, Gumpper RH, Sakamoto K, Dewran Kocak D, Olsen RHJ, Huang XP, Zhang S, Huang KL, Zaidi SA, Nguyen MT , Jo MJ, Katritch V, Fay JF, Scherrer G, Roth BL
(2024) Cell , 187 , 7433 - 7449.e20
PUBMED: 39631393
DOI: doi:10.1016/j.cell.2024.11.001
ISSN: 1097-4172