EMD-45601

Single-particle
3.54 Å
EMD-45601
3D View Gallery
Deposition: 02/07/2024
Map released: 08/01/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45601

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cht summary report (pdf.gz) Map-9cht FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human E3 ligase E6AP in complex with HPV16-E6 and p53

EMD-45601

Single-particle
3.54 Å
EMD-45601
3D View Gallery
Deposition: 02/07/2024
Map released: 08/01/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human papillomavirus 16
Sample: Ternary complex of E6AP with viral factor E6 and neosubstrate p53
Fitted models: 9cht

Deposition Authors: Kenny S , Das C
Structure of E6AP in complex with HPV16-E6 and p53 reveals a novel ordered domain important for E3 ligase activation.
Kenny S , Iyer S, Gabel CA, Tegenfeldt N, DeMarco AG, Hall MC, Chang L, Davisson VJ , Pol SV, Das C
(2025) Structure , 33 , 504 - 516.e4
PUBMED: 39818213
DOI: doi:10.1016/j.str.2024.12.013
ISSN: 0969-2126
ASTM: STRUE6