EMD-45578

Single-particle
2.94 Å
EMD-45578
3D View Gallery
Deposition: 28/06/2024
Map released: 02/07/2025
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45578

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cg9 summary report (pdf.gz) Map-9cg9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of an HMGB1 box bound to nucleosome at SHL-2

EMD-45578

Single-particle
2.94 Å
EMD-45578
3D View Gallery
Deposition: 28/06/2024
Map released: 02/07/2025
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xenopus laevis, Homo sapiens, synthetic construct
Sample: Complex of nucleosome with HMGB1
Fitted models: 9cg9

Deposition Authors: Chio US , Saunders HS, Narlikar GJ , Cheng Y
HMGB1 deforms nucleosomal DNA to generate a dynamic chromatin environment counteracting the effects of linker histone.
Saunders HS, Chio US , Moore CM , Ramani V , Cheng Y , Narlikar GJ
(2025) Sci Adv , 11 , eads4473 - eads4473
PUBMED: 40815652
DOI: doi:10.1126/sciadv.ads4473
ISSN: 2375-2548