EMD-45568

Single-particle
3.37 Å
EMD-45568
3D View Gallery
Deposition: 28/06/2024
Map released: 19/02/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45568

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cg4 summary report (pdf.gz) Map-9cg4 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of FAN1, PCNA and DNA substrate with (CAG)2 extrusion in intermediate state

EMD-45568

Single-particle
3.37 Å
EMD-45568
3D View Gallery
Deposition: 28/06/2024
Map released: 19/02/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, synthetic construct
Sample: Ternary complex of FAN1-PCNA-DNA in intermediate state
Fitted models: 9cg4

Deposition Authors: Li F , Pluciennik A
Structural and molecular basis of PCNA-activated FAN1 nuclease function in DNA repair.
Li F , Phadte AS , Bhatia M, Barndt S , Monte Carlo Iii AR , Hou CD , Yang R, Strock S, Pluciennik A
(2025) Nat Commun , 16 , 4411 - 4411
PUBMED: 40368897
DOI: doi:10.1038/s41467-025-59323-y
ISSN: 2041-1723