EMD-45465

Helical reconstruction
3.3 Å
EMD-45465
3D View Gallery
Deposition: 24/06/2024
Map released: 27/11/2024
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45465

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cda summary report (pdf.gz) Map-9cda FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of type I-2 alpha-synuclein filament from multiple system atrophy

EMD-45465

Helical reconstruction
3.3 Å
EMD-45465
3D View Gallery
Deposition: 24/06/2024
Map released: 27/11/2024
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Type I-2 alpha-synuclein filament from multiple system atrophy
Fitted models: 9cda

Deposition Authors: Yan NL , Candido F, Tse E , Melo AA , Southworth DR , Merz GE
Cryo-EM structure of a novel alpha-synuclein filament subtype from multiple system atrophy.
Yan NL , Candido F, Tse E , Melo AA , Prusiner SB , Mordes DA , Southworth DR , Paras NA , Merz GE
(2025) FEBS Lett , 599 , 33 - 40
PUBMED: 39511911
DOI: doi:10.1002/1873-3468.15048
ISSN: 0014-5793
ASTM: FEBLAL
Grant Support: