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EMD-45426

Single-particle
3.2 Å
EMD-45426
3D View Gallery
Deposition: 19/06/2024
Map released: 11/09/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45426
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cbm summary report (pdf.gz) Map and 9cbm FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of dexmedetomidine-bound alpha-2A-adrenergic receptor in complex with heterotrimeric Gi-protein

EMD-45426

Single-particle
3.2 Å
EMD-45426
3D View Gallery
Deposition: 19/06/2024
Map released: 11/09/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Rattus norvegicus
Sample: Dexmedetomidine-bound alpha-2A-adrenergic receptor in complex with heterotrimeric Gi-protein
Fitted models: 9cbm

Deposition Authors: Lou JS , Su M, Wang J, Do HN, Miao Y, Huang XY
Distinct binding conformations of epinephrine with alpha- and beta-adrenergic receptors.
Lou JS , Su M, Wang J, Do HN, Miao Y, Huang XY
(2024) Exp.Mol.Med. , 56 , 1952 - 1966
PUBMED: 39218975
DOI: doi:10.1038/s12276-024-01296-x
ISSN: 1226-3613