EMD-4536

Single-particle
3.9 Å
EMD-4536
3D View Gallery
Deposition: 07/01/2019
Map released: 27/02/2019
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4536

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6qee summary report (pdf.gz) Map-6qee FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.

EMD-4536

Single-particle
3.9 Å
EMD-4536
3D View Gallery
Deposition: 07/01/2019
Map released: 27/02/2019
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Nanodisc reconstituted ABCB1HM (human mouse chimeric ABCB1) EQ mutant in complex with UIC2 Fab and zosuquidar
Fitted models: 6qee

Deposition Authors: Alam A , Alam A
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
Alam A , Kowal J , Broude E, Roninson I , Locher KP
(2019) Science , 363 , 753 - 756
PUBMED: 30765569
DOI: doi:10.1126/science.aav7102
ISSN: 1095-9203
ASTM: SCIEAS
Grant Support: