EMD-45279

Single-particle
3.1 Å
EMD-45279
3D View Gallery
Deposition: 10/06/2024
Map released: 24/09/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45279

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9c7c summary report (pdf.gz) Map-9c7e summary report (pdf.gz) Map-9c7c FULL report (pdf.gz) Map-9c7e FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation

EMD-45279

Single-particle
3.1 Å
EMD-45279
3D View Gallery
Deposition: 10/06/2024
Map released: 24/09/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Aequorea victoria, Rattus norvegicus
Sample: Diheteromeric NMDA receptor GluN1/GluN2A in nanodisc, in complex with glycine, glutamate, and GNE-4123
Fitted models: 9c7c, 9c7e

Deposition Authors: Jalali-Yazdi F , Kim J , Gouaux E
Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements.
Abbott JA , Kim J , Liu B , Popescu GK , Gouaux E , Jalali-Yazdi F
(2025) Sci Adv , 11 , eadx4647 - eadx4647
PUBMED: 40991709
DOI: doi:10.1126/sciadv.adx4647
ISSN: 2375-2548