EMD-45193
V-Shaped, Channel Formed, T2a Nanobody Bound conformation of wild-type human CFTR (sharpened map from cryoSPARC non-uniform refinement)
EMD-45193
Single-particle2.99 Å
Deposition: 05/06/2024Map released: 02/07/2025
Last modified: 02/07/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: Wild-type human CFTR solubilized in digitonin and cholesterol-hemisuccinate plus T2a nanobody in the presence of 2 mM MgATP
Deposition Authors: Hunt JF
,
Paige AS
,
Cohen BM
,
Goldberg PM
,
Wang C
,
Loughlin BJ
,
Kappes JC
,
Yang Z
,
Jiang F
,
Govaerts C
,
Overtus M
,
Rich Z
Sample: Wild-type human CFTR solubilized in digitonin and cholesterol-hemisuccinate plus T2a nanobody in the presence of 2 mM MgATP
Deposition Authors: Hunt JF
,
Paige AS
,
Cohen BM
,
Goldberg PM
,
Wang C
,
Loughlin BJ
,
Kappes JC
,
Yang Z
,
Jiang F
,
Govaerts C
,
Overtus M
,
Rich Z
V-Shaped, Channel Formed, T2a Nanobody Bound conformation of wild-type human CFTR (sharpened map from cryoSPARC non-uniform refinement)
Hunt FJ,
Paige AS
,
Cohen BM
,
Goldberg PM
,
Wang C
,
Loughlin BJ
,
Kappes JC
,
Yang Z
,
Jiang F
,
Govaerts C
,
Overtus M
,
Urbatsch IL,
Lukacs G
To Be Published
,
Cohen BM
,
Goldberg PM
,
Wang C
,
Loughlin BJ
,
Kappes JC
,
Yang Z
,
Jiang F
,
Govaerts C
,
Overtus M
,
Urbatsch IL,
Lukacs G
To Be Published
Grant Support:
