EMD-45154

Single-particle
2.9 Å
EMD-45154
3D View Gallery
Deposition: 30/05/2024
Map released: 09/10/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45154
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9c2c summary report (pdf.gz) Map and 9c2c FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human P2X1 receptor in the NF449-bound inhibited state

EMD-45154

Single-particle
2.9 Å
EMD-45154
3D View Gallery
Deposition: 30/05/2024
Map released: 09/10/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Membrane protein
Fitted models: 9c2c

Deposition Authors: Oken AC , Lisi NE, Ditter IA , Shi H , Mansoor SE , Mansoor SE
Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding.
Oken AC , Lisi NE, Ditter IA , Shi H , Nechiporuk NA, Mansoor SE
(2024) Nat Commun , 15 , 8490 - 8490
PUBMED: 39353889
DOI: doi:10.1038/s41467-024-52636-4
ISSN: 2041-1723