EMD-45083

Single-particle
2.6 Å
EMD-45083
3D View Gallery
Deposition: 25/05/2024
Map released: 12/02/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45083

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9c0g summary report (pdf.gz) Map-9c0g FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Phosphorylated human NKCC1 in complex with torsemide

EMD-45083

Single-particle
2.6 Å
EMD-45083
3D View Gallery
Deposition: 25/05/2024
Map released: 12/02/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Phosphorylated human NKCC1 in complex with torsemide
Fitted models: 9c0g

Deposition Authors: Zhao YX, Cao EH
Structural basis for human NKCC1 inhibition by loop diuretic drugs.
Zhao Y , Vidossich P, Forbush B, Ma J , Rinehart J , De Vivo M, Cao E
(2025) EMBO J , 44 , 1540 - 1562
PUBMED: 39875725
DOI: doi:10.1038/s44318-025-00368-6
ISSN: 1460-2075
ASTM: EMJODG