EMD-44930

Single-particle
2.9 Å
EMD-44930
3D View Gallery
Deposition: 19/05/2024
Map released: 11/06/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44930
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bv3 summary report (pdf.gz) Map and 9bv3 FULL report (pdf.gz)
EMICSS annotations (xml)

M1B Midnolin-Proteasome

EMD-44930

Single-particle
2.9 Å
EMD-44930
3D View Gallery
Deposition: 19/05/2024
Map released: 11/06/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 26 proteasome with degron-fused midnolin
Fitted models: 9bv3

Deposition Authors: Gao J, Yip MCJ, Shao S
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma.
Nardone C, Gao J, Seo HS, Mintseris J, Ort L, Yip MCJ, Negasi M, Besschetnova AK, Kamitaki N, Gygi SP, Dhe-Paganon S, Munshi NC, Fulciniti M, Greenberg ME, Shao S, Elledge SJ, Gu X
(2025) Mol Cell , 85 , 2597 - 2609.e11
PUBMED: 40532701
DOI: doi:10.1016/j.molcel.2025.05.030
ISSN: 1097-2765
ASTM: MOCEFL