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EMD-44919
Single particle CryoEM structure of the Pf80S ribosome in the rotated-2 PRE state (rt state with P and E-site tRNA)
EMD-44919
Single-particle2.8 Å
Deposition: 17/05/2024Map released: 28/05/2025
Last modified: 10/12/2025
Sample Organism:
Plasmodium falciparum 3D7
Sample: Plasmodium falciparum 80S ribosome in non-rotated state with E-site tRNA
Fitted models: 9but
Deposition Authors: Haile M, Anton L
,
Ho CM
Sample: Plasmodium falciparum 80S ribosome in non-rotated state with E-site tRNA
Fitted models: 9but
Deposition Authors: Haile M, Anton L
,
Ho CM
Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug.
Anton L ,
Cheng W,
Haile MT,
Dziekan JM,
Cobb DW,
Zhu X,
Han L,
Li E,
Nair A,
Lee CL,
Wang H,
Ke H,
Zhang G,
Doud EH,
Cowman AF,
Ho CM
(2025) Nat Struct Mol Biol , 32 , 2158 - 2164
,
Cheng W,
Haile MT,
Dziekan JM,
Cobb DW,
Zhu X,
Han L,
Li E,
Nair A,
Lee CL,
Wang H,
Ke H,
Zhang G,
Doud EH,
Cowman AF,
Ho CM
(2025) Nat Struct Mol Biol , 32 , 2158 - 2164
Grant Support:
- National Institutes of Health/Office of the Director: DP5OD029613 (United States)
- Swiss National Science Foundation: P2BSP3_200205 (Switzerland)
- Human Frontier Science Program (HFSP): LT000452/2021-L (France)