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EMD-44918
Single particle CryoEM structure of the Pf80S ribosome in the unloaded state (nrt with E-site tRNA)
EMD-44918
Single-particle2.4 Å
Deposition: 17/05/2024Map released: 28/05/2025
Last modified: 10/12/2025
Sample Organism:
Plasmodium falciparum 3D7
Sample: Sucrose gradient purified 80S ribosome from P. falciparum
Fitted models: 9bus
Deposition Authors: Haile M, Anton L
,
Ho CM
Sample: Sucrose gradient purified 80S ribosome from P. falciparum
Fitted models: 9bus
Deposition Authors: Haile M, Anton L
,
Ho CM
Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug.
Anton L ,
Cheng W,
Haile MT,
Dziekan JM,
Cobb DW,
Zhu X,
Han L,
Li E,
Nair A,
Lee CL,
Wang H,
Ke H,
Zhang G,
Doud EH,
Cowman AF,
Ho CM
(2025) Nat Struct Mol Biol , 32 , 2158 - 2164
,
Cheng W,
Haile MT,
Dziekan JM,
Cobb DW,
Zhu X,
Han L,
Li E,
Nair A,
Lee CL,
Wang H,
Ke H,
Zhang G,
Doud EH,
Cowman AF,
Ho CM
(2025) Nat Struct Mol Biol , 32 , 2158 - 2164
Grant Support:
- National Institutes of Health/Office of the Director: DP5OD029613 (United States)
- Swiss National Science Foundation: P2BSP3_200205 (Switzerland)
- Human Frontier Science Program (HFSP): LT000452/2021-L (France)