EMD-44906
Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation
EMD-44906
Single-particle2.5 Å
Deposition: 16/05/2024Map released: 23/04/2025
Last modified: 29/10/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation
Fitted models: 9bud
Deposition Authors: Cao J
,
Belousoff MJ ,
Johnson RM ,
Sexton PM,
Wootten DL
Sample: Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation
Fitted models: 9bud
Deposition Authors: Cao J
,
Belousoff MJ ,
Johnson RM ,
Sexton PM,
Wootten DL
Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors.
Cao J ,
Belousoff MJ ,
Johnson RM ,
Keov P,
Mariam Z,
Deganutti G,
Christopoulos G,
Hick CA,
Reedtz-Runge S,
Glendorf T,
Ballarin-Gonzalez B,
Raun K,
Bayly-Jones C,
Wootten D,
Sexton PM
(2025) Nat Commun , 16 , 3389 - 3389
,
Belousoff MJ ,
Johnson RM ,
Keov P,
Mariam Z,
Deganutti G,
Christopoulos G,
Hick CA,
Reedtz-Runge S,
Glendorf T,
Ballarin-Gonzalez B,
Raun K,
Bayly-Jones C,
Wootten D,
Sexton PM
(2025) Nat Commun , 16 , 3389 - 3389
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1154434 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2025694 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1155302 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2026300 (Australia)
- Australian Research Council (ARC): IC200100052 (Australia)