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EMD-44800

Single-particle
2.55 Å
EMD-44800
3D View Gallery
Deposition: 09/05/2024
Map released: 29/01/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44800
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bqi summary report (pdf.gz) Map and 9bqi FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of BAY-1797 bound to the full-length human P2X4 receptor in the closed state

EMD-44800

Single-particle
2.55 Å
EMD-44800
3D View Gallery
Deposition: 09/05/2024
Map released: 29/01/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Membrane protein
Fitted models: 9bqi

Deposition Authors: Shi H , Ditter IA , Oken AC , Mansoor SE , Godsey MH, Mansoor SE
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.
Shi H , Ditter IA , Oken AC , Mansoor SE
(2025) Sci Adv , 11 , eadr3315 - eadr3315
PUBMED: 39823330
DOI: doi:10.1126/sciadv.adr3315
ISSN: 2375-2548