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EMD-44766

Single-particle
3.21 Å
EMD-44766
3D View Gallery
Deposition: 07/05/2024
Map released: 28/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44766
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bpa summary report (pdf.gz) Map and 9bpa FULL report (pdf.gz)
EMICSS annotations (xml)

Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form

EMD-44766

Single-particle
3.21 Å
EMD-44766
3D View Gallery
Deposition: 07/05/2024
Map released: 28/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human DNA polymerase theta helicase domain in complex with inhibitor AB25583
Fitted models: 9bpa

Deposition Authors: Ito F , Li Z, Chen XS
Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Ito F , Li Z, Minakhin L, Chandramouly G, Tyagi M, Betsch R, Krais JJ , Taberi B, Vekariya U, Calbert M , Skorski T, Johnson N , Chen XS , Pomerantz RT
(2024) Nat Commun , 15 , 7003 - 7003
PUBMED: 39143110
DOI: doi:10.1038/s41467-024-51351-4
ISSN: 2041-1723