EMD-44765

Single-particle
3.21 Å
EMD-44765
3D View Gallery
Deposition: 07/05/2024
Map released: 28/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44765

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9bp9 summary report (pdf.gz) Map-9bp9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form

EMD-44765

Single-particle
3.21 Å
EMD-44765
3D View Gallery
Deposition: 07/05/2024
Map released: 28/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human DNA polymerase theta helicase domain in complex with inhibitor AB25583
Fitted models: 9bp9

Deposition Authors: Ito F , Li Z, Chen XS
Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Ito F , Li Z, Minakhin L, Chandramouly G, Tyagi M, Betsch R, Krais JJ , Taberi B, Vekariya U, Calbert M , Skorski T, Johnson N , Chen XS , Pomerantz RT
(2024) Nat Commun , 15 , 7003 - 7003
PUBMED: 39143110
DOI: doi:10.1038/s41467-024-51351-4
ISSN: 2041-1723