EMD-44747
A broadly-neutralizing antibody against Ebolavirus glycoprotein that can potentiate the breadth and neutralization potency of other anti-glycoprotein antibodies
EMD-44747
Single-particle3.0 Å
Deposition: 05/05/2024Map released: 05/11/2025
Last modified: 20/05/2026
Sample Organism:
Oryctolagus cuniculus,
Ebolavirus,
Ebola virus
Sample: Zaire Ebola Glycoprotein dTM (GP1 and GP2 including MLD) complexed with 11883 and 11886
Fitted models: 9bop
Deposition Authors: Donnellan FR, Rayaprolu V, Rijal P, O'Dowd V, Parvate A, Callaway H, Hariharan C, Parekh D, Hui S
,
Shaffer K,
Hastie K,
Shimanski L,
Muller-Krauter H,
Stecker T,
Balaram A,
Halfmann P,
Saphire EO,
Lightwood DJ,
Townsend AR,
Draper SJ
Sample: Zaire Ebola Glycoprotein dTM (GP1 and GP2 including MLD) complexed with 11883 and 11886
Fitted models: 9bop
Deposition Authors: Donnellan FR, Rayaprolu V, Rijal P, O'Dowd V, Parvate A, Callaway H, Hariharan C, Parekh D, Hui S
,
Shaffer K,
Hastie K,
Shimanski L,
Muller-Krauter H,
Stecker T,
Balaram A,
Halfmann P,
Saphire EO,
Lightwood DJ,
Townsend AR,
Draper SJ
A broadly-neutralizing antibody against Orthoebolavirus glycoprotein that potentiates the breadth and neutralization of other antibodies.
Donnellan FR,
Rayaprolu V,
Rijal P,
O'Dowd V,
Parvate A,
Callaway H,
Hariharan C,
Parekh D,
Hui S ,
Shaffer KCL,
Avalos RD,
Hastie KM,
Schimanski L,
Muller-Krauter H,
Strecker T,
Balaram A,
Halfmann P,
Saphire EO,
Lightwood DJ,
Townsend AR,
Draper SJ
(2026) Npj Viruses
,
Shaffer KCL,
Avalos RD,
Hastie KM,
Schimanski L,
Muller-Krauter H,
Strecker T,
Balaram A,
Halfmann P,
Saphire EO,
Lightwood DJ,
Townsend AR,
Draper SJ
(2026) Npj Viruses
Grant Support:
- Medical Research Council (MRC, United Kingdom): MR/N01796X/1 (United Kingdom)