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EMD-44678
Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
EMD-44678
Single-particle3.2 Å
Deposition: 01/05/2024Map released: 16/04/2025
Last modified: 29/10/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
Fitted models: 9blw
Deposition Authors: Cao J
,
Belousoff MJ
,
Sexton PM
,
Wootten DL
Sample: Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
Fitted models: 9blw
Deposition Authors: Cao J
,
Belousoff MJ
,
Sexton PM
,
Wootten DL
Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors.
Cao J
,
Belousoff MJ
,
Johnson RM,
Keov P
,
Mariam Z,
Deganutti G
,
Christopoulos G
,
Hick CA
,
Reedtz-Runge S
,
Glendorf T
,
Ballarin-Gonzalez B
,
Raun K
,
Bayly-Jones C
,
Wootten D
,
Sexton PM
(2025) Nat Commun , 16 , 3389 - 3389
,
Belousoff MJ
,
Johnson RM,
Keov P
,
Mariam Z,
Deganutti G
,
Christopoulos G
,
Hick CA
,
Reedtz-Runge S
,
Glendorf T
,
Ballarin-Gonzalez B
,
Raun K
,
Bayly-Jones C
,
Wootten D
,
Sexton PM
(2025) Nat Commun , 16 , 3389 - 3389
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1154434 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2025694 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1155302 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2026300 (Australia)
- Australian Research Council (ARC): IC200100052 (Australia)
