EMD-44678
Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
EMD-44678
Single-particle3.2 Å
Deposition: 01/05/2024Map released: 16/04/2025
Last modified: 29/10/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
Fitted models: 9blw
Deposition Authors: Cao J
,
Belousoff MJ ,
Sexton PM ,
Wootten DL
Sample: Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
Fitted models: 9blw
Deposition Authors: Cao J
,
Belousoff MJ ,
Sexton PM ,
Wootten DL
Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors.
Cao J ,
Belousoff MJ ,
Johnson RM,
Keov P ,
Mariam Z,
Deganutti G ,
Christopoulos G ,
Hick CA ,
Reedtz-Runge S ,
Glendorf T ,
Ballarin-Gonzalez B ,
Raun K ,
Bayly-Jones C ,
Wootten D ,
Sexton PM
(2025) Nat Commun , 16 , 3389 - 3389
,
Belousoff MJ ,
Johnson RM,
Keov P ,
Mariam Z,
Deganutti G ,
Christopoulos G ,
Hick CA ,
Reedtz-Runge S ,
Glendorf T ,
Ballarin-Gonzalez B ,
Raun K ,
Bayly-Jones C ,
Wootten D ,
Sexton PM
(2025) Nat Commun , 16 , 3389 - 3389
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1154434 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2025694 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1155302 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2026300 (Australia)
- Australian Research Council (ARC): IC200100052 (Australia)