EMD-44671
The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex
EMD-44671
Single-particle3.9 Å
Deposition: 30/04/2024Map released: 04/09/2024
Last modified: 01/07/2026
Sample Organism:
Homo sapiens
Sample: Pdcd4-40S-eIF4A-eIF3-eIF1 complex
Fitted models: 9bln
Deposition Authors: Brito Querido J
,
Sokabe M ,
Diaz-Lopez I ,
Gordiyenko Y,
Zuber P,
Yifei D,
Albacete-Albacete L,
Ramakrishnan V ,
S Fraser C
Sample: Pdcd4-40S-eIF4A-eIF3-eIF1 complex
Fitted models: 9bln
Deposition Authors: Brito Querido J
,
Sokabe M ,
Diaz-Lopez I ,
Gordiyenko Y,
Zuber P,
Yifei D,
Albacete-Albacete L,
Ramakrishnan V ,
S Fraser C
Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Brito Querido J ,
Sokabe M ,
Diaz-Lopez I ,
Gordiyenko Y,
Zuber P,
Du Y ,
Albacete-Albacete L,
Ramakrishnan V ,
Fraser CS
(2024) Nat Commun , 15 , 6633 - 6633
,
Sokabe M ,
Diaz-Lopez I ,
Gordiyenko Y,
Zuber P,
Du Y ,
Albacete-Albacete L,
Ramakrishnan V ,
Fraser CS
(2024) Nat Commun , 15 , 6633 - 6633
Grant Support:
- UK Research and Innovation (UKRI): MC_U105184332 (United Kingdom)
- Wellcome Trust: WT096570 (United Kingdom)
- Louis-Jeantet Foundation: (Switzerland)