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EMD-44643

Single-particle
2.51 Å
EMD-44643
3D View Gallery
Deposition: 29/04/2024
Map released: 22/05/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44643
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bkk summary report (pdf.gz) Map and 9bkk FULL report (pdf.gz)
EMICSS annotations (xml)

Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex

EMD-44643

Single-particle
2.51 Å
EMD-44643
3D View Gallery
Deposition: 29/04/2024
Map released: 22/05/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of CCK1R (sterol 7M mutant) bound to miniGs (Gq, Gi chimera), G-beta1, G-gamma-2 and CCK8s.
Fitted models: 9bkk

Deposition Authors: Harikumar KG, Zhao P, Cary BP , Xu X , Desai AJ, Mobbs JI, Toufaily C, Furness SGB, Christopoulos A, Belousoff MJ, Wootten D , Sexton PM, Miller LJ
Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.
Harikumar KG, Zhao P, Cary BP , Xu X , Desai AJ, Dong M, Mobbs JI, Toufaily C, Furness SGB, Christopoulos A, Belousoff MJ, Wootten D , Sexton PM, Miller LJ
(2024) PLoS Biol , 22 , e3002673 - e3002673
PUBMED: 39083706
DOI: doi:10.1371/journal.pbio.3002673
ISSN: 1545-7885