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EMD-44627

Single-particle
2.8 Å
EMD-44627
3D View Gallery
Deposition: 24/04/2024
Map released: 05/03/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44627
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bj2 summary report (pdf.gz) Map and 9bj2 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the SARS-CoV-2 S 6P trimer complex with the human neutralizing antibody Fab fragment, C1533 (local refinement of NTD and C1533)

EMD-44627

Single-particle
2.8 Å
EMD-44627
3D View Gallery
Deposition: 24/04/2024
Map released: 05/03/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: SARS-CoV-2 S 6P + C1533 Fab Fragments
Fitted models: 9bj2

Deposition Authors: Rubio AA , Abernathy ME , Barnes CO
Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern.
Rubio AA , Baharani VA, Dadonaite B , Parada M , Abernathy ME , Wang Z , Lee YE , Eso MR, Phung J , Ramos I , Chen T , El Nesr G , Bloom JD , Bieniasz PD , Nussenzweig MC , Barnes CO
(2025) Sci Transl Med , 17 , eadq5720 - eadq5720
PUBMED: 40043139
DOI: doi:10.1126/scitranslmed.adq5720
ISSN: 1946-6242
Grant Support: