Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-44595
Structure of VRC44.01 Fab in complex with 3BNC117-purified C1080.c3 RnS SOSIP.664 HIV-1 Env trimer
EMD-44595
Single-particle2.83 Å
Deposition: 23/04/2024Map released: 13/11/2024
Last modified: 01/01/2025
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: VRC44 and 3BNC117 Fabs with Repaired C1080 Env trimer
Fitted models: 9bio
Deposition Authors: Gorman J, Kwong PD
Sample: VRC44 and 3BNC117 Fabs with Repaired C1080 Env trimer
Fitted models: 9bio
Deposition Authors: Gorman J, Kwong PD
A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies.
Cale EM,
Shen CH,
Olia AS,
Radakovich NA,
Rawi R,
Yang Y,
Ambrozak DR,
Bennici AK,
Chuang GY,
Crooks ED,
Driscoll JI,
Lin BC,
Louder MK,
Madden PJ,
Messina MA,
Osawa K,
Stewart-Jones GBE,
Verardi R,
Vrakas Z,
Xie D,
Zhang B,
Binley JM,
Connors M,
Koup RA,
Pierson TC ,
Doria-Rose NA,
Kwong PD ,
Mascola JR,
Gorman J
(2024) Cell Rep , 43 , 115010 - 115010
,
Doria-Rose NA,
Kwong PD ,
Mascola JR,
Gorman J
(2024) Cell Rep , 43 , 115010 - 115010
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM103310 (United States)
- Simons Foundation: SF349247 (United States)