EMD-44585

Single-particle
3.0 Å
EMD-44585
3D View Gallery
Deposition: 23/04/2024
Map released: 16/10/2024
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44585

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9bia summary report (pdf.gz) Map-9bia FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of NINJ1 K45Q bound to Nb538

EMD-44585

Single-particle
3.0 Å
EMD-44585
3D View Gallery
Deposition: 23/04/2024
Map released: 16/10/2024
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, synthetic construct
Sample: Complex of NINJ1 with Nb538
Fitted models: 9bia

Deposition Authors: Pourmal S , Johnson MC, Deshpande I
Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture.
Pourmal S , Truong ME , Johnson MC, Yang Y, Zhou L, Alegre K, Stowe IB, Gupta S , Chen PA, Zhang Y, Rohou A , Newton K , Kayagaki N , Dixit VM , Deshpande I
(2025) Nature , 637 , 446 - 452
PUBMED: 39476863
DOI: doi:10.1038/s41586-024-08273-4
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: