Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-44550

Single-particle
2.9 Å
EMD-44550
3D View Gallery
Deposition: 21/04/2024
Map released: 22/01/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44550
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bhm summary report (pdf.gz) Map and 9bhm FULL report (pdf.gz)
EMICSS annotations (xml)

Human proton sensing receptor GPR68 in complex with miniGs

EMD-44550

Single-particle
2.9 Å
EMD-44550
3D View Gallery
Deposition: 21/04/2024
Map released: 22/01/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Complex of GPR68 bound to Gs heterotrimer
Fitted models: 9bhm

Deposition Authors: Howard MK, Hoppe N, Huang XP, Macdonald CB , Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A
Molecular basis of proton sensing by G protein-coupled receptors.
Howard MK, Hoppe N, Huang XP, Mitrovic D, Billesbolle CB, Macdonald CB , Mehrotra E, Rockefeller Grimes P, Trinidad DD, Delemotte L, English JG, Coyote-Maestas W, Manglik A
(2025) Cell , 188 , 671
PUBMED: 39753132
DOI: doi:10.1016/j.cell.2024.11.036
ISSN: 1097-4172