EMD-44537

Single-particle
3.5 Å
EMD-44537
3D View Gallery
Deposition: 19/04/2024
Map released: 01/05/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44537

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9bh9 summary report (pdf.gz) Map-9bh9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation

EMD-44537

Single-particle
3.5 Å
EMD-44537
3D View Gallery
Deposition: 19/04/2024
Map released: 01/05/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human DNA polymerase theta helicase domain bound to stem-loop DNA with microhomology in the 3' overhang
Fitted models: 9bh9

Deposition Authors: Zerio CJ, Lander GC
Human polymerase theta helicase positions DNA microhomologies for double-strand break repair.
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
(2025) Nat Struct Mol Biol , 32 , 1061 - 1068
PUBMED: 40021738
DOI: doi:10.1038/s41594-025-01514-8
ISSN: 1545-9985