EMD-44500

Single-particle
2.71 Å
EMD-44500
3D View Gallery
Deposition: 18/04/2024
Map released: 08/05/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44500

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9bfm summary report (pdf.gz) Map-9bfm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor

EMD-44500

Single-particle
2.71 Å
EMD-44500
3D View Gallery
Deposition: 18/04/2024
Map released: 08/05/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Escherichia coli K-12
Sample: H6PD
Fitted models: 9bfm

Deposition Authors: Su CC
Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment.
Allgood SC, Su CC, Crooks AL, Meyer CT , Zhou B , Betterton MD, Barbachyn MR, Yu EW , Detweiler CS
(2023) mBio , 14 , e0249223
PUBMED: 37921493
DOI: doi:10.1073/pnas.1901346116
ISSN: 2150-7511