EMD-44491
Cryo-EM structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab
EMD-44491
Single-particle4.5 Å
Deposition: 16/04/2024Map released: 31/07/2024
Last modified: 23/10/2024
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: Cryo-EM Structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab
Fitted models: 9bf6
Deposition Authors: Gorman J
,
Kwong PD
Sample: Cryo-EM Structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab
Fitted models: 9bf6
Deposition Authors: Gorman J
,
Kwong PD
Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Zhang P,
Gorman J ,
Tsybovsky Y,
Lu M,
Liu Q ,
Gopan V,
Singh M,
Lin Y,
Miao H,
Seo Y,
Kwon A,
Olia AS,
Chuang GY,
Geng H,
Lai YT,
Zhou T,
Mascola JR,
Mothes W,
Kwong PD ,
Lusso P
(2024) Cell Rep , 43 , 114518 - 114518
,
Tsybovsky Y,
Lu M,
Liu Q ,
Gopan V,
Singh M,
Lin Y,
Miao H,
Seo Y,
Kwon A,
Olia AS,
Chuang GY,
Geng H,
Lai YT,
Zhou T,
Mascola JR,
Mothes W,
Kwong PD ,
Lusso P
(2024) Cell Rep , 43 , 114518 - 114518
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM103310 (United States)
- Simons Foundation: SF349247 (United States)