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EMD-44482
Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab
EMD-44482
Single-particle4.1 Å
Deposition: 16/04/2024Map released: 31/07/2024
Last modified: 13/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: Cryo-EM Structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab
Fitted models: 9ber
Deposition Authors: Gorman J
,
Kwong PD
Sample: Cryo-EM Structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab
Fitted models: 9ber
Deposition Authors: Gorman J
,
Kwong PD
Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Zhang P,
Gorman J ,
Tsybovsky Y,
Lu M,
Liu Q,
Gopan V,
Singh M,
Lin Y,
Miao H,
Seo Y,
Kwon A,
Olia AS,
Chuang GY,
Geng H,
Lai YT,
Zhou T,
Mascola JR,
Mothes W,
Kwong PD ,
Lusso P
(2024) Cell Rep , 43 , 114518 - 114518
,
Tsybovsky Y,
Lu M,
Liu Q,
Gopan V,
Singh M,
Lin Y,
Miao H,
Seo Y,
Kwon A,
Olia AS,
Chuang GY,
Geng H,
Lai YT,
Zhou T,
Mascola JR,
Mothes W,
Kwong PD ,
Lusso P
(2024) Cell Rep , 43 , 114518 - 114518
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM103310 (United States)
- Simons Foundation: SF349247 (United States)