EMD-44387

Single-particle
2.7 Å
EMD-44387
3D View Gallery
Deposition: 02/04/2024
Map released: 05/02/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44387

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9b9k summary report (pdf.gz) Map-9b9k FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Integrin alpha-5 beta-1 in complex with MINT1526A Fab

EMD-44387

Single-particle
2.7 Å
EMD-44387
3D View Gallery
Deposition: 02/04/2024
Map released: 05/02/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, unidentified
Sample: Protein complex of integrin alpha-5 beta-1 with MINT1526A Fab
Fitted models: 9b9k

Deposition Authors: Nguyen A, Azumaya CM, Campbell MG
Shared ligand-blocking mechanism but distinct conformational modulation by alpha 5-targeting antibodies BIIG2 and MINT1526A.
Nguyen A, Heim JB, Cordara G, Chan MC, Johannesen H, Charlesworth C, Li M, Azumaya CM, Madden B, Krengel U, Meves A, Campbell MG
(2025) bioRxiv
PUBMED: 39829743
DOI: doi:10.1101/2025.01.08.631572
ISSN: 2692-8205