EMD-44191

Single-particle
3.74 Å
EMD-44191
3D View Gallery
Deposition: 21/03/2024
Map released: 26/03/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44191

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9b4y summary report (pdf.gz) Map-9b4y FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of importin alpha-1/beta bound to TDP-43

EMD-44191

Single-particle
3.74 Å
EMD-44191
3D View Gallery
Deposition: 21/03/2024
Map released: 26/03/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Importin Alpha1/Beta/TDP-43 trimeric complex
Fitted models: 9b4y

Deposition Authors: Ko Y, Cingolani G
Single Acetylation-mimetic Mutation in TDP-43 Nuclear Localization Signal Disrupts Importin alpha 1/ beta Signaling.
Ko YH, Lokareddy RK , Doll SG , Yeggoni DP, Girdhar A, Mawn I, Klim JR , Rizvi NF, Meyers R, Gillilan RE , Guo L, Cingolani G
(2024) J Mol Biol , 436 , 168751 - 168751
PUBMED: 39181183
DOI: doi:10.1016/j.jmb.2024.168751
ISSN: 1089-8638
ASTM: JMOBAK