Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-44133

Helical reconstruction
3.2 Å
EMD-44133
3D View Gallery
Deposition: 18/03/2024
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44133
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9b3a summary report (pdf.gz) Map and 9b3a FULL report (pdf.gz)
EMICSS annotations (xml)

filament of type 1 KD-mxyl miniature tau macrocycle derived from 4R tauopathic fold

EMD-44133

Helical reconstruction
3.2 Å
EMD-44133
3D View Gallery
Deposition: 18/03/2024
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: type 1 KD-mxyl miniature tau macrocycle derived from 4R tauopathic fold
Fitted models: 9b3a

Deposition Authors: Xu X , Angera JI, Rajewski HB, Jiang W , Del Valle RJ
Macrocyclic beta-arch peptides that mimic the structure and function of disease-associated tau folds.
Angera IJ , Xu X , Rajewski BH , Hallinan GI, Zhang X, Ghetti B, Vidal R , Jiang W , Del Valle JR
(2025) Nat Chem , 17 , 865 - 874
PUBMED: 40307419
DOI: doi:10.1038/s41557-025-01805-z
ISSN: 1755-4349