Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-44123

Single-particle
3.5 Å
EMD-44123
3D View Gallery
Deposition: 18/03/2024
Map released: 05/06/2024
Last modified: 26/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44123
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Cryo-EM density of GluK2 amino-terminal domain (GluK2-ATD) from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to ConA

EMD-44123

Single-particle
3.5 Å
EMD-44123
3D View Gallery
Deposition: 18/03/2024
Map released: 05/06/2024
Last modified: 26/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: full-length rat GluK2 tetramer in complex with two concanavalin A dimers

Deposition Authors: Nadezhdin KD , Gangwar SP , Sobolevsky AI
Kainate receptor channel opening and gating mechanism.
Gangwar SP , Yelshanskaya MV, Nadezhdin KD , Yen LY, Newton TP , Aktolun M , Kurnikova MG , Sobolevsky AI
(2024) Nature , 630 , 762 - 768
PUBMED: 38778115
DOI: doi:10.1038/s41586-024-07475-0
ISSN: 1476-4687
ASTM: NATUAS