EMD-43983

Single-particle
4.4 Å
EMD-43983
3D View Gallery
Deposition: 07/03/2024
Map released: 13/11/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43983

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The map of the bent AlphaIIbBeta3 in complex with R21D10 Fab

EMD-43983

Single-particle
4.4 Å
EMD-43983
3D View Gallery
Deposition: 07/03/2024
Map released: 13/11/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: The semi-extended AlphaIIbBeta3 in complex with R21D10 Fab

Deposition Authors: Wang JL, Walz T , Coller B, Wang L , Li JH
An alpha IIb beta 3 monoclonal antibody traps a semiextended conformation and allosterically inhibits large ligand binding.
Wang L , Wang J , Li J, Walz T , Coller BS
(2024) Blood Adv , 8 , 4398 - 4409
PUBMED: 38968144
DOI: doi:10.1182/bloodadvances.2024013177
ISSN: 2473-9537