EMD-43969

Single-particle
3.3 Å
EMD-43969
3D View Gallery
Deposition: 06/03/2024
Map released: 13/11/2024
Last modified: 27/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43969

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9axl summary report (pdf.gz) Map-9axl FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the semi-extended AlphaIIbBeta3 in complex with R21D10 Fab

EMD-43969

Single-particle
3.3 Å
EMD-43969
3D View Gallery
Deposition: 06/03/2024
Map released: 13/11/2024
Last modified: 27/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: The semi-extended AlphaIIbBeta3 in complex with R21D10 Fab
Fitted models: 9axl

Deposition Authors: Wang JL, Walz T , Coller B, Wang L , Li JH
An alpha IIb beta 3 monoclonal antibody traps a semiextended conformation and allosterically inhibits large ligand binding.
Wang L , Wang J , Li J, Walz T , Coller BS
(2024) Blood Adv , 8 , 4398 - 4409
PUBMED: 38968144
DOI: doi:10.1182/bloodadvances.2024013177
ISSN: 2473-9537