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EMD-43842
VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)
EMD-43842
Single-particle3.1 Å
Deposition: 28/02/2024Map released: 16/10/2024
Last modified: 25/12/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: BA.2.86 Spike glycoprotein in complex with VIR-7229 Fab
Fitted models: 9au2
Deposition Authors: Tortorici MA
,
Park YJ ,
Veelser D,
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Sample: BA.2.86 Spike glycoprotein in complex with VIR-7229 Fab
Fitted models: 9au2
Deposition Authors: Tortorici MA
,
Park YJ ,
Veelser D,
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification.
Rosen LE,
Tortorici MA ,
De Marco A,
Pinto D,
Foreman WB,
Taylor AL,
Park YJ ,
Bohan D,
Rietz T,
Errico JM,
Hauser K,
Dang HV,
Chartron JW,
Giurdanella M,
Cusumano G,
Saliba C,
Zatta F,
Sprouse KR,
Addetia A,
Zepeda SK,
Brown J,
Lee J,
Dellota Jr E,
Rajesh A ,
Noack J,
Tao Q,
DaCosta Y,
Tsu B,
Acosta R,
Subramanian S,
de Melo GD ,
Kergoat L,
Zhang I,
Liu Z,
Guarino B,
Schmid MA,
Schnell G,
Miller JL,
Lempp FA,
Czudnochowski N,
Cameroni E,
Whelan SPJ,
Bourhy H,
Purcell LA,
Benigni F,
di Iulio J,
Pizzuto MS,
Lanzavecchia A,
Telenti A,
Snell G,
Corti D,
Veesler D,
Starr TN
(2024) Cell , 187 , 7196
,
De Marco A,
Pinto D,
Foreman WB,
Taylor AL,
Park YJ ,
Bohan D,
Rietz T,
Errico JM,
Hauser K,
Dang HV,
Chartron JW,
Giurdanella M,
Cusumano G,
Saliba C,
Zatta F,
Sprouse KR,
Addetia A,
Zepeda SK,
Brown J,
Lee J,
Dellota Jr E,
Rajesh A ,
Noack J,
Tao Q,
DaCosta Y,
Tsu B,
Acosta R,
Subramanian S,
de Melo GD ,
Kergoat L,
Zhang I,
Liu Z,
Guarino B,
Schmid MA,
Schnell G,
Miller JL,
Lempp FA,
Czudnochowski N,
Cameroni E,
Whelan SPJ,
Bourhy H,
Purcell LA,
Benigni F,
di Iulio J,
Pizzuto MS,
Lanzavecchia A,
Telenti A,
Snell G,
Corti D,
Veesler D,
Starr TN
(2024) Cell , 187 , 7196
Grant Support: