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EMD-43786

Single-particle
4.0 Å
EMD-43786
3D View Gallery
Deposition: 23/02/2024
Map released: 22/01/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43786
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9arl summary report (pdf.gz) Map and 9arl FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum strain A1-ST7B, major class

EMD-43786

Single-particle
4.0 Å
EMD-43786
3D View Gallery
Deposition: 23/02/2024
Map released: 22/01/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Clostridium botulinum A, Clostridium botulinum A str. Hall
Sample: Ternary complex of M-PTC/A1-ST7B with OrfX2/A1-ST7B, major class
Fitted models: 9arl

Deposition Authors: Gao L
Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47.
Gao L, Nowakowska MB , Selby K, Przykopanski A, Chen B, Kruger M , Douillard FP, Lam KH, Chen P , Huang T, Minton NP, Dorner MB , Dorner BG, Rummel A , Lindstrom M , Jin R
(2025) Nat Struct Mol Biol , 32 , 864 - 875
PUBMED: 39838108
DOI: doi:10.1038/s41594-024-01479-0
ISSN: 1545-9985