EMD-43751

Single-particle
2.45 Å
EMD-43751
3D View Gallery
Deposition: 20/02/2024
Map released: 17/04/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43751

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8w2l summary report (pdf.gz) Map-8w2l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TRPM7 structure in complex with anticancer agent CCT128930 in closed state

EMD-43751

Single-particle
2.45 Å
EMD-43751
3D View Gallery
Deposition: 20/02/2024
Map released: 17/04/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Complex of TRPM7 with antagonist CCT128930
Fitted models: 8w2l

Deposition Authors: Nadezhdin KD, Sobolevsky AI
Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930.
Nadezhdin KD, Correia L, Shalygin A, Aktolun M, Neuberger A , Gudermann T, Kurnikova MG, Chubanov V , Sobolevsky AI
(2024) Cell Rep , 43 , 114108 - 114108
PUBMED: 38615321
DOI: doi:10.1016/j.celrep.2024.114108
ISSN: 2211-1247