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EMD-43667
Soluble ectodomain of human cytomegalovirus (HCMV) glycoprotein B (gB) in the postfusion conformation in complex with 1G2 and 7H3 Fabs
EMD-43667
Single-particle3.4 Å
Deposition: 09/02/2024Map released: 18/09/2024
Last modified: 04/06/2025
Sample Organism:
Homo sapiens,
Human betaherpesvirus 5
Sample: Soluble ectodomain of human cytomegalovirus (HCMV) glycoprotein B (gB) in the postfusion conformation in complex with 1G2 and 7H3 Fabs
Fitted models: 8vym
Deposition Authors: Sponholtz MR
,
Byrne PO ,
McLellan JS
Sample: Soluble ectodomain of human cytomegalovirus (HCMV) glycoprotein B (gB) in the postfusion conformation in complex with 1G2 and 7H3 Fabs
Fitted models: 8vym
Deposition Authors: Sponholtz MR
,
Byrne PO ,
McLellan JS
Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation.
Sponholtz MR ,
Byrne PO ,
Lee AG ,
Ramamohan AR ,
Goldsmith JA,
McCool RS ,
Zhou L ,
Johnson NV ,
Hsieh CL,
Connors M ,
Karthigeyan KP,
Crooks CM ,
Fuller AS,
Campbell JD,
Permar SR,
Maynard JA ,
Yu D,
Bottomley MJ ,
McLellan JS
(2024) PNAS , 121 , e2404250121 - e2404250121
,
Byrne PO ,
Lee AG ,
Ramamohan AR ,
Goldsmith JA,
McCool RS ,
Zhou L ,
Johnson NV ,
Hsieh CL,
Connors M ,
Karthigeyan KP,
Crooks CM ,
Fuller AS,
Campbell JD,
Permar SR,
Maynard JA ,
Yu D,
Bottomley MJ ,
McLellan JS
(2024) PNAS , 121 , e2404250121 - e2404250121
Grant Support: