EMD-43663

Single-particle
3.9 Å
EMD-43663
3D View Gallery
Deposition: 08/02/2024
Map released: 12/02/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43663

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vyk summary report (pdf.gz) Map-8vyk FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of full-length human cardiac sodium channel - Class-II.

EMD-43663

Single-particle
3.9 Å
EMD-43663
3D View Gallery
Deposition: 08/02/2024
Map released: 12/02/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mammalia, Homo sapiens
Sample: Sodium channel protein type 5 subunit alpha
Fitted models: 8vyk

Deposition Authors: Biswas R , Chinthalapudi K
Structural basis of human Na v 1.5 gating mechanisms.
Biswas R , Lopez-Serrano AL , Purohit A , Ramirez-Navarro A, Huang HL, Grandinetti G, Cheng X , Heissler SM , Deschenes I , Chinthalapudi K
(2025) PNAS , 122 , e2416181122 - e2416181122
PUBMED: 40366698
DOI: doi:10.1073/pnas.2416181122
ISSN: 1091-6490
ASTM: PNASA6