Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-43653
Kappa opioid receptor:Galphai protein in complex with inverse agonist GB18, Original map receptor
EMD-43653
Single-particle3.3 Å
Deposition: 07/02/2024Map released: 05/02/2025
Last modified: 05/02/2025
Sample Organism:
Homo sapiens
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist JDTic
Deposition Authors: Gati C
,
Motiwala Z
,
Tyson AS
,
Styrpejko D
,
Han GW
,
Khan S
,
Ramos-Gonzalez N
,
Shenvi R
,
Majumdar S
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist JDTic
Deposition Authors: Gati C
,
Motiwala Z
,
Tyson AS
,
Styrpejko D
,
Han GW
,
Khan S
,
Ramos-Gonzalez N
,
Shenvi R
,
Majumdar S
Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes.
Tyson AS
,
Khan S
,
Motiwala Z
,
Han GW
,
Zhang Z,
Ranjbar M,
Styrpejko D
,
Ramos-Gonzalez N
,
Woo S
,
Villers K,
Landaker D
,
Kenakin T
,
Shenvi R
,
Majumdar S
,
Gati C
(2025) Nat Chem Biol
,
Khan S
,
Motiwala Z
,
Han GW
,
Zhang Z,
Ranjbar M,
Styrpejko D
,
Ramos-Gonzalez N
,
Woo S
,
Villers K,
Landaker D
,
Kenakin T
,
Shenvi R
,
Majumdar S
,
Gati C
(2025) Nat Chem Biol
Grant Support:
