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EMD-43653

Single-particle
3.3 Å
EMD-43653 Deposition: 07/02/2024
Map released: 05/02/2025
Last modified: 05/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43653

Kappa opioid receptor:Galphai protein in complex with inverse agonist GB18, Original map receptor

EMD-43653

Single-particle
3.3 Å
EMD-43653 Deposition: 07/02/2024
Map released: 05/02/2025
Last modified: 05/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist JDTic

Deposition Authors: Gati C , Motiwala Z , Tyson AS , Styrpejko D , Han GW , Khan S , Ramos-Gonzalez N , Shenvi R , Majumdar S
Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes.
PUBMED: 39775170
DOI: doi:10.1038/s41589-024-01812-0
ISSN: 1552-4469